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KMID : 0854720110310010059
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Korean Journal of Asthma, Allergy and Clinical Immunology
2011 Volume.31 No. 1 p.59 ~ p.62
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A Case of Carbamazepine-induced DRESS Syndrome
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Kim Dong-Ha
Kim In-Su
Park Ju-Hee
Yoo Kwang-Ho
Park Kui-Young
Li Kap-Sok
Seo Seong-Jun
Hong Chang-Kwun
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Abstract
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DRESS (Drug rash with eosinophilia and systemic symptoms) syndrome is a rare and potentially life-threatening drug reaction, which has been associated with aromatic anticonvulsants such as phenytoin, carbamazepine and phenobarbital. It is characterized by hematologic abnormalities, especially eosinophilia and mononucleosis- like atypical lymphocytosis, skin rash, fever, lymph node enlargement and single or multiple organ involvement, which starts within 8 weeks of the initiation of therapy. Despite these characteristic findings, generally clinicians have difficulty finding out culprit drugs. Herein, we report a case of carbamazepine-induced DRESS syndrome which developed erythematous skin eruptions 8 weeks after carbamazepine therapy.
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KEYWORD
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Carbamazepine, DRESS syndrome
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